As he celebrates his birthday on May 6, take a look at images of George Clooney throughout his career.
Clooney got his start in TV, appearing in shows like the short-lived sitcom "E/R," "Roseanne," "Hotel," "The Golden Girls" and "Facts of Life" in the mid-to-late-1980s.
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Matt Porteous/Kensington Palace via CNN
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Russian Federal Space Agency
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