BALTIMORE -- Delmon Young's two-run homer in the first inning gave starter Kevin Gausman all the support he needed, and the right-hander threw six strong innings to help the Baltimore Orioles to a 4-2 victory over the Toronto Blue Jays Thursday night.

Young's homer off Toronto starter Mark Buehrle gave the Orioles a 2-0 lead just two batters in, and Baltimore never trailed. For the eighth game in a row, Toronto's opponent scored first.

Catcher Caleb Joseph added a run-scoring single and right fielder Nick Markakis hit an RBI double for the Orioles, who won for the third time in four games.

Gausman (2-1) allowed one run on five hits and three walks while striking out three. He never set down the Jays in order, and Toronto (39-29) repeatedly got deep into counts, but he was able to avoid major trouble.

Left-hander Brian Matusz (seventh) and right-hander Ryan Webb (eighth) each pitched an inning before left-hander Zach Britton threw a scoreless ninth for his sixth save.

Buehrle (10-3) lost for the second start in a row after becoming the majors' first 10-game winner this year. He gave up four runs on eight hits in 6 1/3 innings.

Left fielder Melky Cabrera and first baseman Edwin Encarnacion drove in the Blue Jays' runs.

Buehrle came into the game with the second-best ERA in the American League, but the Orioles got to him quickly. Right fielder Nick Markakis led off with a single in the first, and Young, Baltimore's designated hitter, followed with his two-run homer.

The Orioles made it 3-0 in the second. Third baseman Manny Machado led off with a double to right and eventually scored on Joseph's single.

Toronto put runners on base in each of the first five innings but didn't break through until the fifth.

Third baseman Juan Francisco led off with a double and moved to third on center fielder Anthony Gose's sacrifice bunt. Francisco then scored when Cabrera lined a two-out single to center, cutting the lead to 3-1.

NOTES: The Orioles signed their top three draft picks -- LHP Brian Gonzalez (third round), RHP Pat Connaughton (fourth round) and RHP David Hess (fifth round). They lost picks in the first two rounds because of free agent signings. ... Baltimore isn't sure yet about its next move with RHP Miguel Gonzalez, who is on the disabled list with an oblique strain. He could pitch with the Orioles as early as Sunday out of the bullpen or as a starter, or he could take another turn in the minors on rehab. ... Toronto OF Colby Rasmus (back) began a rehab stint with Triple-A Buffalo on Thursday. He went 1-for-3 with a walk as the designated hitter. ... The Jays are struggling on offense, having scored three runs or fewer in each their past seven games.